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News

Emmyon scientists discover fundamental molecular mechanism of skeletal muscle atrophy

Aug 19, 2016 By redilson

Click to view article

August 19, 2016, Coralville, IA – In collaboration with colleagues at the University of Iowa and the Buck Institute for Research on Aging, Emmyon scientists Chris Adams, Scott Ebert and Mike Dyle published a new paper today describing a previously unknown mechanism of skeletal muscle atrophy.

The paper, entitled “Gadd45a promotes skeletal muscle atrophy by forming a complex with the protein kinase MEKK4” was published in The Journal of Biological Chemistry.  The paper was selected as a JBC Paper of the Week and was selected for the journal cover.  To view the paper, please click here.

Filed Under: News

Emmyon scientists discover small molecules that reduce muscle loss and weakness during aging

Jan 3, 2016 By redilson

September 3, 2015, Coralville, IA. – Emmyon scientists Scott Ebert, John Talley and Christopher Adams published a new paper today describing ursolic acid and tomatidine as natural compounds that reduce muscle loss and weakness during aging. The paper, published in The Journal of Biological Chemistry, may be found here.

Filed Under: News

Emmyon research covered in Chemical and Engineering News

Jan 3, 2016 By redilson

September 21, 2015, Washington D.C. – Emmyon research was featured today in Chemical and Engineering News, a publication of the American Chemical Society. The article, “Chemical Fountain of Youth Explained,” may be found below:

Ursolic-Acid-Tomatidine-C&EN-2015

Filed Under: News

Emmyon scientists publish review article describing their small molecule discovery work

Apr 8, 2015 By redilson

March 24, 2015, Coralville, IA. – Emmyon scientists Chris Adams and Scott Ebert were invited to write a new paper that summarizes their research to date on ursolic acid and tomatidine. The paper, published in Current Opinion in Clinical Nutrition and Metabolic Care, may be found here.

Filed Under: News

Emmyon scientists discover new molecular mechanisms of skeletal muscle atrophy

Apr 8, 2015 By redilson

January 15, 2015, Iowa City, IA. – Emmyon scientists Chris Adams and Scott Ebert have co-authored two new papers describing novel molecular mechanisms of skeletal muscle atrophy. The research was performed in the Adams laboratory at the University of Iowa.

The first paper identifies two proteins (p53 and ATF4) that work together to cause muscle atrophy when muscles are immobilized (American Journal of Physiology – Endocrinology and Metabolism, volume 307, pages E245-261).

The second paper identifies a protein (spermine oxidase) that helps to protect muscle from atrophy (American Journal of Physiology – Endocrinology and Metabolism, volume 308, pages E144-158).

Understanding basic mechanisms of skeletal muscle atrophy helps us find new ways to combat it.

Filed Under: News

Emmyon receives Phase I STTR award from the National Institute on Aging

Jul 8, 2014 By redilson

July 8, 2014, Coralville, IA. – Emmyon is pleased to announce that it has received a new Phase I STTR award from the National Institute on Aging.  The funding will support research to discover and develop pharmaceutical compounds that improve muscle mass, function and metabolism.

Filed Under: News

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